The Emblaser and various 'streaming' programs (which communicate with the Emblaser) will work on both Mac and PC.
Compatibility issues arise with the software used to generate the cutting / engraving files. Both Cut2D-Laser and the Picengrave range of software are Windows only programs.
The easiest way to reliably run this software on a Mac is via Bootcamp, Parallels or VMware, which allows customers to run Windows on their Mac computers.
As a convenience to Mac users, we have created a 'Mac-Friendly' version of Cut2D-Laser which can be run natively on a OSX but this is not supported by the software developer, Vectric.
See this article for more information: Link